@article{10.25259/MEDINDIA_8_2022, title = {Significance of biochemical and hematological indicators in predicting COVID-19 prognosis during the omicron variant phase – A retrospective study}, author = {Gandhi, Khushi and Khare, Shalini and Sachdeva, Ruchi}, abstract = { Objectives: Severe acute respiratory syndrome (SARS-CoV-2) causes a multiorgan disease affecting the respiratory, gastrointestinal, nervous, and other systems of the body. Omicron infections increased exponentially during the third wave of SARS-CoV-2 infection in India which started in December 2021. Omicron is a variant of SARS-CoV-2. It has a high transmission rate and the ability to escape immunity. A range of biochemical and hematological indicators can aid in determining the severity of the infection and the need for prompt treatment. Materials and Methods: During January and February 2022, 492 confirmed cases of COVID were evaluated for biomarkers such as neutrophil-lymphocyte ratio (NLR), D-dimer, inflammatory indicators such as interleukin-6, C-reactive protein (CRP), lactate dehydrogenase (LDH), and ferritin. Result: The present study revealed a correlation between SARS-CoV-2 infection, possibly Omicron and elevated levels of NLR, CRP, LDH, and ferritin. Hematological aberrations such as anemia, erythrocytopenia, neutrophilia, lymphocytopenia, and thrombocytopenia were also observed in some cases. Conclusion: Biochemical and hematological markers such as CRP LDH, Ferritin and NLR are important parameters in the prognosis of SARS-CoV-2 infection including Omicron infections. }, volume = 1, pages = {11}, journal = {Medicine India}, issn = {2831-7890}, url = {https://doi.org/10.25259/MEDINDIA_8_2022}, doi = {10.25259/MEDINDIA_8_2022} }